Medicina clinica · 1998
[The usefulness of the desensitization to rifampin in the treatment of mycobacterial disease in patients with AIDS].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Arrizabalaga J, Casas A, Camino X, Iribarren J A, Rodríguez Arrondo F, Von Wichmann M A
Аннотация
BACKGROUND: Hypersensitivity reactions to rifampin are relatively uncommon, but they may result in cessation of therapeutic medications.
PATIENTS AND METHODS: We report our experience with oral desensitization protocol to rifampin in a group of 35 HIV-positive patients with mycobacterial disease who had some hypersensitivity reaction to this drug.
RESULTS: Adverse reactions with this protocol were few and easily treated.
CONCLUSIONS: Oral desensitization to rifampin is safe and effective, allowing some of these patients (60%) to reintroduce the drug and to reduce the time of treatment.
PATIENTS AND METHODS: We report our experience with oral desensitization protocol to rifampin in a group of 35 HIV-positive patients with mycobacterial disease who had some hypersensitivity reaction to this drug.
RESULTS: Adverse reactions with this protocol were few and easily treated.
CONCLUSIONS: Oral desensitization to rifampin is safe and effective, allowing some of these patients (60%) to reintroduce the drug and to reduce the time of treatment.