Head & neck · 2025
Long-Term Outcomes and Social Reintegration After Salvage Open Partial Horizontal Laryngectomy Type II/III for Radiation Failure.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Miyamoto Shunsuke, Kano Koichi, Tsutsumi Shohei, Momiyama Kaho, Hagiwara Kohei, Matsuki Takashi, Yamashita Taku
Аннотация
BACKGROUND: The long-term outcomes and social reintegration following open partial horizontal laryngectomy (OPHL) type II/III after radiation failure remain unclear. This study aimed to evaluate the outcomes of salvage OPHL.
METHODS: We retrospectively analyzed 56 recurrent cases after radiotherapy and 84 unirradiated cases who underwent OPHL type II/III at Kitasato University Hospital between November 1997 and October 2023. Overall survival (OS), disease-free survival (DFS), larynx preservation (LP), laryngo-esophageal dysfunction-free survival (LEDFS), and return to work (RTW) were evaluated.
RESULTS: At 10 years, OS, DFS, LP, and LEDFS were 76%, 73%, 93%, and 67% in recurrent cases and 65%, 58%, 94%, and 58% in unirradiated cases, with no significant difference. RTW rates were 87% and 81%, respectively (p = 0.57).
CONCLUSIONS: OPHL type II/III after radiation failure demonstrated favorable long-term outcomes and RTW rates, supporting its role as a valuable salvage option.
METHODS: We retrospectively analyzed 56 recurrent cases after radiotherapy and 84 unirradiated cases who underwent OPHL type II/III at Kitasato University Hospital between November 1997 and October 2023. Overall survival (OS), disease-free survival (DFS), larynx preservation (LP), laryngo-esophageal dysfunction-free survival (LEDFS), and return to work (RTW) were evaluated.
RESULTS: At 10 years, OS, DFS, LP, and LEDFS were 76%, 73%, 93%, and 67% in recurrent cases and 65%, 58%, 94%, and 58% in unirradiated cases, with no significant difference. RTW rates were 87% and 81%, respectively (p = 0.57).
CONCLUSIONS: OPHL type II/III after radiation failure demonstrated favorable long-term outcomes and RTW rates, supporting its role as a valuable salvage option.