Medicina clinica · 1999
[Serum lipoproteins in patients with porphyria cutanea tarda].
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Fernández-Miranda C, de la Calle M, Gómez Izquierdo M T, Larumbe S, Enríquez de Salamanca R
Аннотация
BACKGROUND: To know the lipid profile in patients with porphyria cutanea tarda (PCT).
PATIENTS AND METHODS: Serum lipoproteins have been studied in 64 males with PCT: 42 with chronic hepatitis C and 22 seronegatives for hepatitis B and C virus. Thirteen patients without porphyria, but with chronic hepatitis C, and 13 healthy subjects were also studied.
RESULTS: Patients with chronic hepatitis C, with or without PCT, had a decrease of total and VLDL cholesterol (TC and VLDLc) and apolipoprotein (apo) B in comparison with healthy controls and seronegative for hepatitis C virus patients with PCT.
CONCLUSIONS: Lipid abnormalities found in PCT are not related with this disease, but with the presence of chronic hepatitis C often associated to PCT.
PATIENTS AND METHODS: Serum lipoproteins have been studied in 64 males with PCT: 42 with chronic hepatitis C and 22 seronegatives for hepatitis B and C virus. Thirteen patients without porphyria, but with chronic hepatitis C, and 13 healthy subjects were also studied.
RESULTS: Patients with chronic hepatitis C, with or without PCT, had a decrease of total and VLDL cholesterol (TC and VLDLc) and apolipoprotein (apo) B in comparison with healthy controls and seronegative for hepatitis C virus patients with PCT.
CONCLUSIONS: Lipid abnormalities found in PCT are not related with this disease, but with the presence of chronic hepatitis C often associated to PCT.