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Медицинская библиотека · Salud publica de Mexico · 1995

[The immunological phenotyping of the lymphocytes in HIV+ patients].

Alvarado-Alemán F J, Kumate-Rodríguez J

Сравнительное исследованиеАннотация на английскомСтатьяПеревод пока не подготовлен

Аннотация

We propose that the ratios of lymphocyte subsets: CD4+/CD8+, CD4+/CD3+, and CD8+/CD3+, graphically displayed in this order, could be an easy way of immunophenotyping and a simple form of interpretation both for clinicians and patients. A total of 187 asymptomatic HIV-positive patients, -including 83 symptomatic patients with AIDS- and a normal comparative age group of 36 patients, were studied by flow cytometry. Ratios were graphically displayed on millimetric-grid paper, and a specific point was given to each obtained ratio. The points were connected by a line. The angles formed by the lines were measured and graphically displayed over a circle. The point of reference 0 degree was located on the left side of the circle, giving the corresponding 90 degrees, 180 degrees, and 240 degrees angles. The graph of the control group shows a "beach chair" image. As soon as the CD4+ lymphocytes diminish and the CD8+ lymphocytes increase in HIV+ patients, "the chair's headrest" descends and the "chair's footpiece" swivels back. Given the ranks and fluctuations of the lymphocyte subsets, their graphic display provides a better representation of the immunological status.

Для цитирования: Alvarado-Alemán F J, Kumate-Rodríguez J. [The immunological phenotyping of the lymphocytes in HIV+ patients].. Salud publica de Mexico. 1995.

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