[The immunomodulating effect of vilozen in the combined treatment of children with rheumatism associated with an allergy].

Effects were traced out of vilosene alone and combination with ketotifene on clinical-and-immunologic parameters in 86 children with rheumatism associated with concurrent allergy. There has been disclosed immunomodulating effect of vilosene in hyposuppressor variant of a secondary immune deficient state in rheumatic children. Antiallergic action of vilosene is more pronounced when employed in combination with ketotifene. The clinical effect was evident 1-1.5 weeks earlier than in controls. The data obtained suggest vilosene and ketotifen to be useful in the treatment of rheumatic children presenting with concurrent allergy.