[The effect of emotional stress on the efficacy of chemotherapy in experimental trichochephaliasis].

In DBA/2st mice experimentally infected with Trichocephalus muris the emotional stress caused by a cat that was placed for 2 hours twice a day during 14 days or more was found to reduce the efficiency of specific drug therapy with albendasole. At the same time there was an increase in the ED84:ED16 ratio (the effective dose of the drug which allows 84 or 16% of helminths to be eliminated), which decreased elimination probability in the whole helminth populations.