Photodiagnosis and photodynamic therapy · 2022
Analysis of choroidal vascularity index in multiple sclerosis patients without optic neuritis attack.
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Temel Emine, Aşıkgarip Nazife, Koçak Yusuf, Örnek Kemal, Kocamış Özkan, Özcan Gökçen
Аннотация
BACKGROUND: To evaluate the choroidal structural changes in multiple sclerosis (MS) patients without previous optic neuritis (ON) attacks.
METHODS: Forty eyes of 20 MS patients without a history of ON and 40 eyes of 20 age-matched healthy volunteers were included in this study. The choroidal thickness (CT) was measured at three points; subfoveal, 1500 µm nasal to the fovea, and 1500 µm temporal to the fovea. Choroidal area (CA), luminal area (LA), and choroidal vascularity index (CVI) were calculated using ImageJ.
RESULTS: The mean subfoveal, nasal and temporal CT were decreased in MS patients compared to controls (for all, p < 0.001). The mean LA was 0.572 ± 0.113 mm2 in MS group, and 0.729 ± 0.188 mm2 in controls (p = 0.002). The mean CVI was decreased in the MS group (69.38% ± 4.87) in comparison to the controls (73.41% ± 5.18) (p = 0.034).
CONCLUSION: The current study demonstrated significant anatomical alterations of the choroid in the eyes of patients with MS.
METHODS: Forty eyes of 20 MS patients without a history of ON and 40 eyes of 20 age-matched healthy volunteers were included in this study. The choroidal thickness (CT) was measured at three points; subfoveal, 1500 µm nasal to the fovea, and 1500 µm temporal to the fovea. Choroidal area (CA), luminal area (LA), and choroidal vascularity index (CVI) were calculated using ImageJ.
RESULTS: The mean subfoveal, nasal and temporal CT were decreased in MS patients compared to controls (for all, p < 0.001). The mean LA was 0.572 ± 0.113 mm2 in MS group, and 0.729 ± 0.188 mm2 in controls (p = 0.002). The mean CVI was decreased in the MS group (69.38% ± 4.87) in comparison to the controls (73.41% ± 5.18) (p = 0.034).
CONCLUSION: The current study demonstrated significant anatomical alterations of the choroid in the eyes of patients with MS.