Revista da Sociedade Brasileira de Medicina Tropical · 2018
Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil.
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Fonseca Ricardo Roberto de Souza, Alves Ana Cláudia Braga Amoras, Amanajás Thalita de Almeida, Nogueira Brenna Magdalena Lima, Menezes Tatiany Oliveira de Alencar, Siravenha Leonardo Quintão, Pereira Danilo Leôncio Aguiar, Machado Luiz Fernando Almeida, Gilet Luciana Campêlo da Silva, Menezes Silvio Augusto Fernandes de
Аннотация
INTRODUCTION: The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated.
METHODS: ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD4 + T lymphocyte count and plasma HIV viral load were obtained from patient records.
RESULTS: CMV DNA was detected in samples of subgingival biofilm in only three individuals, two of them with chronic periodontitis (4%) and one with gingivitis (3.3%).
CONCLUSIONS: The prevalence of CMV is very low both in HIV-1 patients with gingivitis and chronic periodontitis.
METHODS: ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD4 + T lymphocyte count and plasma HIV viral load were obtained from patient records.
RESULTS: CMV DNA was detected in samples of subgingival biofilm in only three individuals, two of them with chronic periodontitis (4%) and one with gingivitis (3.3%).
CONCLUSIONS: The prevalence of CMV is very low both in HIV-1 patients with gingivitis and chronic periodontitis.