Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil.

INTRODUCTION

The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated.

METHODS

ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD4 + T lymphocyte count and plasma HIV viral load were obtained from patient records.

RESULTS

CMV DNA was detected in samples of subgingival biofilm in only three individuals, two of them with chronic periodontitis (4%) and one with gingivitis (3.3%).

CONCLUSIONS

The prevalence of CMV is very low both in HIV-1 patients with gingivitis and chronic periodontitis.