NGENUITY versus ARTEVO 800 in vitreoretinal surgery: A retrospective comparison of two different three-dimensional visualization systems in a French tertiary center.

PURPOSE: Digital heads-up three-dimensional (3D) visualization systems are now familiar in vitreoretinal surgery, with reported better technical and similar patient outcomes compared to conventional microscopes. Here, we compared the efficacy and safety of two different 3D systems.

METHODS

A retrospective, single-center, cohort study of adults having undergone vitrectomy for treatment of rhegmatogenous retinal detachment (RRD), idiopathic epiretinal membrane (ERM), or macular hole (MH). Consecutive vitreoretinal surgeries were performed by the same surgeon using the NGENUITY system (3D-N group) or the ARTEVO 800 system (3D-A group) between April 2021 and November 2023 in our tertiary ophthalmology department (Toulouse University Hospital, France). The primary outcomes were 6-month retinal detachment (RD) recurrence rate, 3-month MH closure rate, and change in central macular thickness (CMT) at 3 months for ERMs.

RESULTS

Two hundred and two surgeries on 202 eyes were included. Surgeries performed were for RRD (n=91/202; 45%), idiopathic ERM (n=82/202; 41%), or MH (n=29/202; 14%). Inclusion was n=121/202(60%) eyes in the 3D-N group and n=81/202(40%) eyes in the 3D-A group. Comparing 3D-N versus 3D-A groups, we found no significant differences in 6-month RD recurrence rate (17% versus 21%; P=0.62), MH closure rate (92% versus 88%; P=1.0), or decrease in CMT at 3 months (-79.5±69.1 versus -68.5±81.2μm; P=0.34). Subgroup analysis according to eyes operated for RRD, idiopathic ERM, or MH showed no significant differences in mean 3-month gains in best-corrected visual acuity, surgery duration, or 3-month post-operative complications between systems used.

CONCLUSION

The two 3D systems were comparable in terms of short-term anatomical and functional outcomes.