Penetrating keratoplasty for pseudophakic bullous keratopathy associated with semiflexible, closed-loop anterior chamber intraocular lenses.

We performed penetrating keratoplasty on 32 eyes that developed pseudophakic bullous keratopathy associated with closed-loop anterior chamber intraocular lenses. All lenses were exchanged at the time of keratoplasty. Seventeen patients received anterior chamber intraocular lenses and 15 patients had a posterior chamber lens sutured to the iris or sclera. Postoperatively, 13 of 32 eyes (41%) achieved a visual acuity of 20/100 or better, and 27 of 32 eyes (84%) had a clear graft. A high incidence of cystoid macular edema (eight cases), and graft rejection (seven cases) resulted in marked visual loss.