A predictive model for early mortality after surgical treatment of heart valve or prosthesis infective endocarditis. The EndoSCORE.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Di Mauro Michele, Dato Guglielmo Mario Actis, Barili Fabio, Gelsomino Sandro, Santè Pasquale, Corte Alessandro Della, Carrozza Antonio, Ratta Ester Della, Cugola Diego, Galletti Lorenzo, Devotini Roger, Casabona Riccardo, Santini Francesco, Salsano Antonio, Scrofani Roberto, Antona Carlo, Botta Luca, Russo Claudio, Mancuso Samuel, Rinaldi Mauro, De Vincentiis Carlo, Biondi Andrea, Beghi Cesare, Cappabianca Giangiuseppe, Tarzia Vincenzo, Gerosa Gino, De Bonis Michele, Pozzoli Alberto, Nicolini Francesco, Benassi Filippo, Rosato Francesco, Grasso Elena, Livi Ugolino, Sponga Sandro, Pacini Davide, Di Bartolomeo Roberto, De Martino Andrea, Bortolotti Uberto, Onorati Francesco, Faggian Giuseppe, Lorusso Roberto, Vizzardi Enrico, Di Giammarco Gabriele, Marinelli Daniele, Villa Emmanuel, Troise Giovanni, Picichè Marco, Musumeci Francesco, Paparella Domenico, Margari Vito, Tritto Francesco, Damiani Girolamo, Scrascia Giuseppe, Zaccaria Salvatore, Renzulli Attilio, Serraino Giuseppe, Mariscalco Giovanni, Maselli Daniele, Foschi Massimiliano, Parolari Alessandro, Nappi Giannantonio, Italian Group of Research for Outcome in Cardiac Surgery (GIROC)
Аннотация
METHODS: From 2000 to 2015, 2715 patients with native valve endocarditis (NVE) or prosthesis valve endocarditis (PVE) were operated on in 26 Italian Cardiac Surgery Centers. The relationship between early mortality and covariates was evaluated with logistic mixed effect models. Fixed effects are parameters associated with the entire population or with certain repeatable levels of experimental factors, while random effects are associated with individual experimental units (centers).
RESULTS: Early mortality was 11.0% (298/2715); At mixed effect logistic regression the following variables were found associated with early mortality: age class, female gender, LVEF, preoperative shock, COPD, creatinine value above 2mg/dl, presence of abscess, number of treated valve/prosthesis (with respect to one treated valve/prosthesis) and the isolation of Staphylococcus aureus, Fungus spp., Pseudomonas Aeruginosa and other micro-organisms, while Streptococcus spp., Enterococcus spp. and other Staphylococci did not affect early mortality, as well as no micro-organisms isolation. LVEF was found linearly associated with outcomes while non-linear association between mortality and age was tested and the best model was found with a categorization into four classes (AUC=0.851).
CONCLUSIONS: The following study provides a logistic risk model to predict early mortality in patients with heart valve or prosthesis infective endocarditis undergoing surgical treatment, called "The EndoSCORE".