International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2009
Effect of cesarean delivery on the endometrium.
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Ben-Nagi Jara, Walker Amy, Jurkovic Davor, Yazbek Joseph, Aplin John D
Аннотация
OBJECTIVE: To compare endometrial tissue samples from cesarean scar (CS) sites and from the posterior uterine wall to better understand the pathophysiology of implantation into a CS.
METHODS: Endometrial samples were taken from both a CS site and the posterior wall in premenopausal women with CSs, and from the posterior wall in premenopausal women who had spontaneous vaginal deliveries (SVDs) only.
RESULTS: In the secretory phase, there were significantly fewer leukocytes at CS sites than in the endometrium of women who had SVDs only (P<0.05). Significant differences in leukocytic infiltration and cell proliferation between the proliferative and secretory phases were only found in women who had SVDs only (P<0.05).
CONCLUSION: Leukocyte recruitment to the endometrium during the secretory phase may be affected by the presence of a CS.
METHODS: Endometrial samples were taken from both a CS site and the posterior wall in premenopausal women with CSs, and from the posterior wall in premenopausal women who had spontaneous vaginal deliveries (SVDs) only.
RESULTS: In the secretory phase, there were significantly fewer leukocytes at CS sites than in the endometrium of women who had SVDs only (P<0.05). Significant differences in leukocytic infiltration and cell proliferation between the proliferative and secretory phases were only found in women who had SVDs only (P<0.05).
CONCLUSION: Leukocyte recruitment to the endometrium during the secretory phase may be affected by the presence of a CS.