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DOI 10.1136/bmjopen-2025-099215

Медицинская библиотека · BMJ open · 2025

Retrospective analysis of value-driven outcomes of diabetic foot ulcer in a tertiary hospital in Singapore.

Chia Adrian Choon Kwang, Tan Ivan En-Howe, Tan Zi Ning, Yeo Wen Jing, Zhao Yun, Yap Charyl Jia Qi, Ang Kwok Ann, Au Marianne Kit Har, Chong Tze Tec

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Аннотация

OBJECTIVE

This study analysed the clinical outcomes and healthcare costs associated with diabetic foot ulcer (DFU) within a tertiary healthcare centre in Singapore.

DESIGN

This is a retrospective, single-centre study. Patient data were extracted from the hospital's electronic health system, including demographic, clinical and hospitalisation information. Hospitalisation costs were categorised into DFU-related and other hospitalisation costs. A one-way sensitivity analysis was performed to estimate the total healthcare costs associated with DFU.

SETTING

Tertiary centre within a population suffering from a diabetic epidemic.

PARTICIPANTS

All patients aged 18 years or older who received DFU treatment between January 2019 and December 2023 at the Singapore General Hospital were included.

RESULTS

A total of 2857 DFU patients were included in the study. In-hospital mortality remained stable at 5%-6% annually. Among the cohort, 39.1% underwent minor amputations, 19.6% had major amputations and 9.0% experienced both minor and major amputations. The median length of stay for surgical patients ranged from 10 (IQR 4-24) to 13 days (IQR 6-31), compared with 4 (IQR 2-8) to 5 (IQR 3-9.5) days for non-surgical patients. Total costs per admission for patients with DFU-related surgery ranged from US$28 588.96 to US$34 204.77, while for those without surgery, costs ranged from US$6637.59 to US$7955.23. Total hospitalisation costs for DFU during the study period ranged from US$65.87 million to US$72.16 million. All figures were inflation adjusted to 2023 US dollars.

CONCLUSIONS

DFU poses a significant clinical and economic burden in Singapore. Understanding the costs associated with DFU is essential for resource allocation and planning in DFU management.

Для цитирования: Chia Adrian Choon Kwang, Tan Ivan En-Howe, Tan Zi Ning, Yeo Wen Jing, Zhao Yun, Yap Charyl Jia Qi, Ang Kwok Ann, Au Marianne Kit Har, Chong Tze Tec. Retrospective analysis of value-driven outcomes of diabetic foot ulcer in a tertiary hospital in Singapore.. BMJ open. 2025. DOI: 10.1136/bmjopen-2025-099215.

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