Invasive sinusitis due to Pseudallescheria boydii in an immunocompetent host.

Chronic invasive sinusitis with Pseudallescheria boydii as the etiologic agent is uncommon but occurs in immunocompetent hosts. We have presented the fourth documented case of sinusitis due to P boydii in a patient without other medical problems. Pseudallescheria is generally sensitive to ketoconazole and not amphotericin B in therapeutic levels. In vitro culture and sensitivity studies are essential in selecting the appropriate antibiotic.