Enuresis in childhood and premature ejaculation in adult life: An enigmatic similarity.

Abstract Objective. To investigate a possible association between enuresis in childhood and premature ejaculation in adult life. Methods. The authors conducted a retrospective study, with two cohorts, consisting of 60 men with premature ejaculation, and 60 comparison subjects who were asked to assess their enuresis in childhood, a history of psychological problems. Results. While 20 (33.3%) subjects with premature ejaculation reported a history of enuresis in childhood, only seven (11.6%) subjects without premature ejaculation had this problem in childhood. Enuresis in childhood was significantly more common in men with a premature ejaculation than controls. While 35 (58.3%) patients with premature ejaculation reported a history of psychological problems, only four (6.6%) controls reported this kind of problems. There was a significant difference between these groups regarding psychological problems. Conclusion. The results of this study suggest that the history of enuresis in childhood seems to increase the risk of having premature ejaculation and psychological problems in adult life. These results lead to a premise that these disorders may share a common etiology and/or neurological pathophysiology.