Electromagnetic indication of hypervigilant responses to emotional stimuli in blood-injection-injury fear.

Blood phobia differs from other phobias and anxiety disorders in that no attentional bias for blood-related stimuli has been consistently observed. The present study aimed at clarifying this characteristic by investigating electromagnetic brain activity to blood-related and -unrelated pictures in high blood-fearful and non-fearful individuals. Relative to non-fearful controls, high blood-fearful subjects displayed more intense occipito-parietal activation 190-250ms after picture onset, which was interpreted as non-specifically enhanced sensory encoding of visual stimuli. Blood-related stimuli did not elicit different activity patterns in high blood-fearful subjects and controls, supporting the hypothesis that non-specific hypervigilance does not provide a basis for subsequent, specifically enhanced processing of fear-related contents.