[Research progress on internal classification and treatment response of chronic rhinosinusitis].

Chronic rhinosinusitis（CRS） is one of the common upper airway disease, which is complex and heterogenerous.It is known that based on clinical observations,CRS phenotype has been classified into CRSwNP and CRSsNP.However, there is still not any uniform standard to differentiate CRS endotype .According to CRS phenotype. The clinical effect of CRS treatment is not satisfied, including bad effects an high reccurence rate because of unclear mechanism.Therefore,it is important to explore CRS endotype,which could help us to recognize the pathologicalmechanism of the disease and to obtain optimal therapies, in order to improve health quality and relieve social burdern.