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DOI 10.3390/jcm15051882

Медицинская библиотека · Journal of clinical medicine · 2026

RAMPA Therapy: Effects on Craniofacial Growth Assessed by Coben Analysis and Statistical Evaluation.

Mitani Yasushi, Okai-Kojima Yuko, Shimazaki Takahisa, Moshfeghi Mohammad, Tonogi Morio, Ogisawa Shouhei, Choi Bumkyoo, Motoyoshi Mitsuru

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Аннотация

Objective

This retrospective comparative cohort study investigated the craniofacial growth effects of the RAMPA (Right Angle Maxillary Protraction Appliance) system. The system aims to protract the maxilla in an anterosuperior direction to address maxillary hypoplasia and skeletal Class III malocclusion, potentially mitigating the posteroinferior displacement often associated with conventional orthopedic approaches. Materials and

Methods

Craniofacial measurements were analyzed before (T1) and after (T2) RAMPA treatment in 30 growing patients (17 males, mean age 7.32 years; 13 females, mean age 8.34 years). Coben analysis was utilized to quantitatively evaluate coordinate relationships and proportional changes based on the Frankfurt Horizontal plane. Statistical significance was determined using paired t-tests or Wilcoxon signed-rank tests (two-sided, α = 0.05) without adjustment for multiple comparisons due to the exploratory nature of the study.

Results

RAMPA treatment was associated with significant increases in facial depth (Ba-N) and anterior facial height (N-Me) in both sexes. Specifically, facial depth increased by an average of 2.65 mm in males (p = 0.001) and 2.18 mm in females (p = 0.007). Female patients showed a significant increase in the maxillary depth ratio (Ptm-A/Ba-N), while males exhibited a significant decrease in the Gonial Angle (avg. 1.47° decrease), suggesting anterior mandibular rotation.

Conclusions

RAMPA treatment effectively promoted anterosuperior craniofacial growth and induced favorable mandibular rotation in this cohort. These findings suggest the system has potential clinical value for improving craniofacial balance in skeletal Class III malocclusion. While improved cervical posture is a theoretical benefit of such remodeling, systemic outcomes were not directly measured in this study.

Для цитирования: Mitani Yasushi, Okai-Kojima Yuko, Shimazaki Takahisa, Moshfeghi Mohammad, Tonogi Morio, Ogisawa Shouhei, Choi Bumkyoo, Motoyoshi Mitsuru. RAMPA Therapy: Effects on Craniofacial Growth Assessed by Coben Analysis and Statistical Evaluation.. Journal of clinical medicine. 2026. DOI: 10.3390/jcm15051882.
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