Enfermedades infecciosas y microbiologia clinica · 1993
[Oro-esophageal candidiasis resistant to fluconazole in patients with AIDS].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Diz P, Ocampo A, Miralles C, Otero I, Iglesias I, Martínez C
Аннотация
BACKGROUND: Fluconazole-resistant Candida albicans has been seldom reported in the literature. in this study, two clinical cases of oro-esophageal candidosis resistant to this antifungal drug are described.
METHOD: Infection was confirmed by isolation of yeasts (culture of mouth swabs, oesophagoscopy and histology of biopsy specimens). In vitro antifungal susceptibility tests were performed with standard methods (NCCLS).
RESULTS: Clinical and microbiological fluconazole-resistant Candida albicans was isolated.
CONCLUSIONS: Causes of development of resistances are commented, and the role of immunodeficiency and the possibility of a Candida strain selection is discussed.
METHOD: Infection was confirmed by isolation of yeasts (culture of mouth swabs, oesophagoscopy and histology of biopsy specimens). In vitro antifungal susceptibility tests were performed with standard methods (NCCLS).
RESULTS: Clinical and microbiological fluconazole-resistant Candida albicans was isolated.
CONCLUSIONS: Causes of development of resistances are commented, and the role of immunodeficiency and the possibility of a Candida strain selection is discussed.