[Evolutionary and transmission characteristics of rabies viruses in Asia].

OBJECTIVE

To understand the rabies virus (RABV) evolutionary relationship between the strains of China and Asia and to know the evolution and transmission characteristics of RABV in Asia.

METHODS

The G sequences of representative strains from China were selected and combined the sequences of other countries in Asia to analyze using BEAST and MigraPhyla software.

RESULTS

The phylogenetic analysis showed that six groups (China I-VI) of China had different epidemic range: China I , II and V groups just cycled in our country; China VI group, from Guangxi and Yunnan provinces, crossed with Southeast Asian strains; China III group and IV group also have closer genetic relationship with Asian country strains.

CONCLUSION

Geographic migration in Asia showed that Thailand and India may be two rabies transmission centers in Asia.