Diffuse hyperplasia of the peribiliary glands.

Diffuse, severe, macroscopically recognizable dilatation and hyperplasia of the peribiliary glands of intrahepatic and extrahepatic bile ducts is an extremely rare condition. To our knowledge, this is the first such case reported in the literature. We encountered this condition in a patient with massive hepatic necrosis. The pathogenesis of the condition is discussed. Unfamiliarity with this pathology could lead to an erroneous diagnosis of a well-differentiated cholangiocarcinoma.