International journal of paleopathology · 2025
A short and sickly life. Multi-indicator analysis of an infant from a late antique Italian burial site (Piano della Civita, Artena, 3rd-5th cent CE).
СтатьяИсторическая статьяКлинический случайПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Cecconi Viola, Nava Alessia, Lugli Federico, Mittnik Alissa, Sawyer Susanna, Gadeyne Jan, Brouillard Cécile, Pinhasi Ron, Reich David, Sperduti Alessandra
Аннотация
OBJECTIVE: To evaluate pathological lesions and related growth impairment in an infant from a late antiquity context in central Italy.
MATERIALS: The individual labeled as 04.AR.60004 comes from a small burial plot in Piano della Civita di Artena, Italy, dated to the 3rd-5th centuries.
METHODS: Macroscopic examination, metric analysis, dental histomorphometry, amelogenin sequencing, and aDNA analyses were employed.
RESULTS: Individual 04.AR.60004 is an infant male with an estimated age-at-death of 2 months showing two metabolic stress events, one occurring before birth and one a few days before death. The well-preserved skeleton shows diffuse abnormal cortical porosity and subperiosteal new bone formation.
CONCLUSIONS: The type and distribution of the skeletal lesions suggest a diagnosis of infantile scurvy, probably associated with a general status of malnutrition. Dimensions of cranial and postcranial bones show a wide discrepancy between the skeletal age (38-40 fetal weeks) and the dental histological age (2 months).
SIGNIFICANCE: Including enamel histology age-at-death estimation may expand our knowledge of the influence of severe pathological cases on growth.
LIMITATIONS: Although scurvy remains the most obvious diagnosis, we cannot exclude other related micronutrient deficiencies which might have affected the individual.
SUGGESTIONS FOR FURTHER RESEARCH: Including dental histometric and molecular sex estimation in infant pathological cases can help us to recognize impaired growth and enhance our understanding of sex-based susceptibility and potential biases in childcare within ancient communities.
MATERIALS: The individual labeled as 04.AR.60004 comes from a small burial plot in Piano della Civita di Artena, Italy, dated to the 3rd-5th centuries.
METHODS: Macroscopic examination, metric analysis, dental histomorphometry, amelogenin sequencing, and aDNA analyses were employed.
RESULTS: Individual 04.AR.60004 is an infant male with an estimated age-at-death of 2 months showing two metabolic stress events, one occurring before birth and one a few days before death. The well-preserved skeleton shows diffuse abnormal cortical porosity and subperiosteal new bone formation.
CONCLUSIONS: The type and distribution of the skeletal lesions suggest a diagnosis of infantile scurvy, probably associated with a general status of malnutrition. Dimensions of cranial and postcranial bones show a wide discrepancy between the skeletal age (38-40 fetal weeks) and the dental histological age (2 months).
SIGNIFICANCE: Including enamel histology age-at-death estimation may expand our knowledge of the influence of severe pathological cases on growth.
LIMITATIONS: Although scurvy remains the most obvious diagnosis, we cannot exclude other related micronutrient deficiencies which might have affected the individual.
SUGGESTIONS FOR FURTHER RESEARCH: Including dental histometric and molecular sex estimation in infant pathological cases can help us to recognize impaired growth and enhance our understanding of sex-based susceptibility and potential biases in childcare within ancient communities.