American journal of veterinary research · 2026
Adjunctive low-level laser therapy improves gingival inflammatory clinical indices, thermographic findings, and systemic cytokines in cats with American Veterinary Dental College stage 1 to 2 periodontal disease.
СтатьяRandomized Controlled Trial, VeterinaryНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Turgut Ferda, Yanmaz Latif Emrah, Ates Muhammed Yasir
Аннотация
OBJECTIVE: To determine whether low-level laser therapy (LLLT), alone or with chlorhexidine (CLX; CLX + LLLT), improves clinical indices of gingival inflammation, gingival temperature, and systemic cytokines compared with CLX alone in cats with early-stage periodontal disease (American Veterinary Dental College stage 1 to 2).
METHODS: Cats diagnosed with American Veterinary Dental College stage 1 to 2 periodontal disease were randomized to 3 groups (CLX, LLLT, and CLX + LLLT; n = 7/group) after full-mouth scaling. Treatments were CLX spray, intraoral 905-nm gallium arsenide LLLT, or both for 7 days. Primary outcomes included probing pocket depth, gingival index, plaque index, and gingival surface temperature. Plasma tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 were secondary outcomes. Thermography and blood sampling were also performed on days 0 and 8.
RESULTS: Mean probing pocket depth decreased by 0.27 mm in CLX, 1.24 mm in LLLT, and 1.20 mm in CLX + LLLT. Gingival index and plaque index declined in all groups, with larger reductions in LLLT-treated cats. Gingival temperature decreased in LLLT (-3.1 °C) and CLX + LLLT (-4.3 °C). Tumor necrosis factor-α decreased in CLX + LLLT (-7.4 ng/L). Interleukin-6 decreased only in CLX + LLLT, and IL-1β changes were negligible.
CONCLUSIONS: LLLT, particularly with CLX, produced greater improvements in gingival inflammatory indices, gingival temperature, and inflammatory markers than CLX alone.
CLINICAL RELEVANCE: LLLT appears to be a safe and effective adjunct for the short-term management of gingival inflammation in cats with early-stage periodontal disease following professional dental cleaning.
METHODS: Cats diagnosed with American Veterinary Dental College stage 1 to 2 periodontal disease were randomized to 3 groups (CLX, LLLT, and CLX + LLLT; n = 7/group) after full-mouth scaling. Treatments were CLX spray, intraoral 905-nm gallium arsenide LLLT, or both for 7 days. Primary outcomes included probing pocket depth, gingival index, plaque index, and gingival surface temperature. Plasma tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 were secondary outcomes. Thermography and blood sampling were also performed on days 0 and 8.
RESULTS: Mean probing pocket depth decreased by 0.27 mm in CLX, 1.24 mm in LLLT, and 1.20 mm in CLX + LLLT. Gingival index and plaque index declined in all groups, with larger reductions in LLLT-treated cats. Gingival temperature decreased in LLLT (-3.1 °C) and CLX + LLLT (-4.3 °C). Tumor necrosis factor-α decreased in CLX + LLLT (-7.4 ng/L). Interleukin-6 decreased only in CLX + LLLT, and IL-1β changes were negligible.
CONCLUSIONS: LLLT, particularly with CLX, produced greater improvements in gingival inflammatory indices, gingival temperature, and inflammatory markers than CLX alone.
CLINICAL RELEVANCE: LLLT appears to be a safe and effective adjunct for the short-term management of gingival inflammation in cats with early-stage periodontal disease following professional dental cleaning.