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DOI 10.1016/j.physio.2025.101867

Медицинская библиотека · Physiotherapy · 2025

Patients' attitudes toward melatonin for musculoskeletal pain: Insights for rehabilitation practice.

Wu Kangchao, Puterflam James, Beckenkamp Paula R, Hall Michelle, Gordon Christopher, Ferreira Manuela L, Grunstein Ron, Ferreira Paulo

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Аннотация

OBJECTIVE

To assess the perceptions and attitudes of individuals with chronic MSK pain toward melatonin as a potential treatment for pain management.

DESIGN

Cross-sectional survey.

SETTING

Nationwide survey conducted via social media platforms and offline advertisements.

PARTICIPANTS

Adults (≥ 18 years) with chronic MSK pain. A total of 254 individuals completed the survey (mean age 60.8 years; 87 % women).

METHODS

Participants completed a custom-designed survey capturing demographics, pain and sleep disturbances, prior melatonin use, and attitudes toward melatonin for pain and sleep.

MAIN OUTCOMES AND MEASURES: Descriptive statistics of melatonin use, perceived effectiveness, concerns, and willingness to use melatonin for pain management.

RESULTS

Sleep disturbances were reported by 73 % of participants, with insomnia most common. Forty percent had previously used melatonin, primarily for sleep, yet 57 % of users were uncertain about its analgesic effects. Willingness to use melatonin was expressed by 79 % of users and 83 % of non-users for pain management. General concerns included side effects, drug interactions, efficacy, and cost.

CONCLUSIONS

While less than half of the participants had used melatonin for sleep, there was a positive attitude towards its use as a potential treatment for MSK pain management. Future high-quality randomised controlled trials are needed to assess the effectiveness of melatonin for MSK pain management. CONTRIBUTION OF PAPER.

Для цитирования: Wu Kangchao, Puterflam James, Beckenkamp Paula R, Hall Michelle, Gordon Christopher, Ferreira Manuela L, Grunstein Ron, Ferreira Paulo. Patients' attitudes toward melatonin for musculoskeletal pain: Insights for rehabilitation practice.. Physiotherapy. 2025. DOI: 10.1016/j.physio.2025.101867.

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