Disseminated Candida parapsilosis infection complicated by native aortic valve endocarditis and peripheral arterial embolization.

Fungal infective endocarditis is a rare but highly morbid condition commonly caused by Candida species. Candida parapsilosis is an uncommon cause of native valve endocarditis and is increasingly associated with healthcare exposure. We report a 50-year-old woman with persistent Candida parapsilosis candidemia complicated by large native aortic valve vegetations and acute limb ischemia from arterial embolization, requiring surgical valve replacement and prolonged antifungal therapy.