Decumbic acid derivatives from soil fungus Lasiodiplodia sp. BG1083.

Phytochemical analysis of Blumea megacephala root soil fungus Lasiodiplodia sp. BG1083 led to the isolation of four decumbic acid derivatives, including a new one phenylethyl ester of decumbic acid (1) and a jasmonic acid analogues, lasiodiplodin acid A (5). Decumbic acid (3) showed the weak antimicrobial activity against Candida albicans with Minimum inhibitory oncentration (MIC) of 128 μg/mL. Lasiodiplodin acid A (5) showed the weak activity against Staphylococcus aureus with MIC of 256 μg/mL.