[Comparative evaluation of the status of neuromuscular transmission and evoked skin sympathetic potential in myasthenia syndrome of the Eaton-Lambert type in patients with and without bronchogenic carcinoma].

Neuromuscular transmission and evoked skin sympathetic potential (ESSP) were examined in 14 patients with Lambert-Eaton syndrome. Bronchogenous lung carcinoma was revealed in four of those patients. No correlation was found between the impairment of neuromuscular transmission and the parameters of ESSP. All the four patients suffering from Lambert-Eaton syndrome combined with bronchogenous lung carcinoma did not manifest ESSP. The reversibility of ESSP disorders established after amiridine and guanidine administration attest to the mediatory character of vegetative regulation impairment in patients with the myasthenic syndrome under discussion.