Gan to kagaku ryoho. Cancer & chemotherapy · 2025
[Pancreatoduodenectomy as Conversion Surgery for Advanced or Recurrent Gastric Cancer-A Report of Six Cases].
СтатьяКлинический случайАннотация на английскомНазвание и аннотация: Перевод пока не подготовлен
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Saito Toshifumi, Ishikawa Hiroyasu, Ishiguro Toru, Sugino Aoi, Irie Naoko, Chiyonobu Norimichi, Shiraishi Takehiro, Ito Tetsuya, Chika Noriyasu, Matsuyama Takatoshi, Kumagai Yoichi, Ishida Hideyuki
Аннотация
Pancreaticoduodenectomy(PD)has been increasingly performed as conversion surgery for advanced gastric cancer. We report 6 cases of gastric cancer in which PD was performed following chemotherapy. The reasons for requiring PD were pancreatic head invasion in 3 cases, common bile duct invasion in 1 case, and lymph node recurrence in the hepatic hilum after distal gastrectomy in 2 cases. Preoperative chemotherapy regimens included S-1+oxaliplatin in 3 cases, S-1+oxaliplatin+ trastuzumab in 1 case, capecitabine+oxaliplatin in 1 case, and S-1+cisplatin in 1 case. One patient died during hospitalization due to sepsis caused by postoperative cholangitis. A pancreatic fistula classified as Clavien-Dindo classification Grade Ⅲa occurred in 1 case. The 1-year and 2-year overall survival rates were 83.3% and 66.7%, respectively. The 1-year and 2- year recurrence-free survival rates were both 75.0%. Although the number of cases is limited, PD as conversion surgery for gastric cancer is considered an effective treatment option.