[The efficiency of alprazolam for seasonal affective disorder (SAD, autumn/winter type)].

We experienced a 49 years old female SAD patient who showed a good response the next day after alprazolam 1.2 mg administration. The back ground EEG of the patient showed a abnormal EEG with slow waves. The personality was colored with historical features. The nadir of body core temperature from rectum slightly delayed in remission phase compared with depressive phase. The patient became hypomania and calmed down gradually. Alprazolam treatment is seemed to be available for SAD patients.