Gemcitabine-induced rectus abdominus radiation recall.

CONTEXT: Radiation recall has been described in the context of gemcitabine chemotherapy. However, this phenomenon has been largely limited to skin.

CASE REPORT: We hereby report a case of radiation recall dermatitis and myositis occurring on gemcitabine monotherapy, five months after completing chemoradiation for locally advanced pancreatic cancer. Radiation recall resolved spontaneously with withdrawal of gemcitabine.

CONCLUSIONS

This is the second case report that describes gemcitabine-induced radiation recall in rectus abdominus muscles after gemcitabine-based radiation therapy. Given the wide use of gemcitabine following chemoradiation for pancreatic cancer, providers should be aware of this potential complication.