Efficiency of topical imiquimod 5% cream in the management of chronic radiation dermatitis with multiple neoplasias.

The immune response modifier imiquimod 5% cream (Aldara) was locally applied to an extensive thoracic chronic radiation dermatitis for 2 weeks on a once daily basis. After moderate to severe irritative reactions with erythema and crusted erosions, areas cleared up within 4 weeks. The patient has now been in complete remission for 2 years.