Dermatology (Basel, Switzerland) · 1996
Efficacy of oral low-dose tretinoin (all-trans-retinoic acid) in lichen planus.
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Ott F, Bollag W, Geiger J M
Аннотация
BACKGROUND: Retinoids were shown to be effective in the treatment of both oral and cutaneous forms of lichen planus.
OBJECTIVE: Confirm the beneficial effect of low doses of oral tretinoin in lichen planus.
METHODS: Eighteen patients with lichen planus were treated in an open study for up to 19 months. Efficacy and safety data were recorded.
RESULTS: Complete remission was observed in 13 (72%) and marked improvement in 4 (22%) out of 18 patients. Six patients showed moderate and 12 had no side effects.
CONCLUSION: Tretinoin is a valuable drug when given at low doses to patients with lichen planus who failed to respond to other therapies.
OBJECTIVE: Confirm the beneficial effect of low doses of oral tretinoin in lichen planus.
METHODS: Eighteen patients with lichen planus were treated in an open study for up to 19 months. Efficacy and safety data were recorded.
RESULTS: Complete remission was observed in 13 (72%) and marked improvement in 4 (22%) out of 18 patients. Six patients showed moderate and 12 had no side effects.
CONCLUSION: Tretinoin is a valuable drug when given at low doses to patients with lichen planus who failed to respond to other therapies.