[Zhonghua yan ke za zhi] Chinese journal of ophthalmology · 1997
[Early corneal limbal autograft transplantation after alkali burns].
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Chen J, Xu J
Аннотация
OBJECTIVES: To understand the clinical significance of corneal limbus transplantation on alkali burns.
METHODS: 14 New Zealand rabbits were used, 1.0 mol/L NaOH solution was placed on the anterior surface of the eyes for 1 minute. Limbal autograft transplantation was performed on 7 rabbits immediately after the burn. The other 7 rabbits were used as controls. The follow-up period lasted for 1 month and then the histopathological changes of corneas were observed under light and scanning electron microscopes.
RESULTS: Faster corneal epithelial healing, less corneal neovascularization and inflammatory cell infiltration occurred in the operative group.
CONCLUSIONS: Early limbal autograft transplantation can accelerate corneal epithelial healing, restrain corneal neovascularization and inflammatory response, therefore it can prevent corneal ulceration.
METHODS: 14 New Zealand rabbits were used, 1.0 mol/L NaOH solution was placed on the anterior surface of the eyes for 1 minute. Limbal autograft transplantation was performed on 7 rabbits immediately after the burn. The other 7 rabbits were used as controls. The follow-up period lasted for 1 month and then the histopathological changes of corneas were observed under light and scanning electron microscopes.
RESULTS: Faster corneal epithelial healing, less corneal neovascularization and inflammatory cell infiltration occurred in the operative group.
CONCLUSIONS: Early limbal autograft transplantation can accelerate corneal epithelial healing, restrain corneal neovascularization and inflammatory response, therefore it can prevent corneal ulceration.