Science advances · 2022
Portable, low-field magnetic resonance imaging enables highly accessible and dynamic bedside evaluation of ischemic stroke.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Yuen Matthew M, Prabhat Anjali M, Mazurek Mercy H, Chavva Isha R, Crawford Anna, Cahn Bradley A, Beekman Rachel, Kim Jennifer A, Gobeske Kevin T, Petersen Nils H, Falcone Guido J, Gilmore Emily J, Hwang David Y, Jasne Adam S, Amin Hardik, Sharma Richa, Matouk Charles, Ward Adrienne, Schindler Joseph, Sansing Lauren, de Havenon Adam, Aydin Ani, Wira Charles, Sze Gordon, Rosen Matthew S, Kimberly W Taylor, Sheth Kevin N
Аннотация
Brain imaging is essential to the clinical management of patients with ischemic stroke. Timely and accessible neuroimaging, however, can be limited in clinical stroke pathways. Here, portable magnetic resonance imaging (pMRI) acquired at very low magnetic field strength (0.064 T) is used to obtain actionable bedside neuroimaging for 50 confirmed patients with ischemic stroke. Low-field pMRI detected infarcts in 45 (90%) patients across cortical, subcortical, and cerebellar structures. Lesions as small as 4 mm were captured. Infarcts appeared as hyperintense regions on T2-weighted, fluid-attenuated inversion recovery and diffusion-weighted imaging sequences. Stroke volume measurements were consistent across pMRI sequences and between low-field pMRI and conventional high-field MRI studies. Low-field pMRI stroke volumes significantly correlated with stroke severity and functional outcome at discharge. These results validate the use of low-field pMRI to obtain clinically useful imaging of stroke, setting the stage for use in resource-limited environments.