Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2004
Nicorandil associated anal ulceration.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Watson A, Suttie S, Fraser A, O'Kelly T, Loudon M
Аннотация
OBJECTIVE: Nicorandil is a vasodilator used to control angina. It has been associated with oral and anal ulceration that resolves upon withdrawal of the drug.
PATIENTS AND METHODS: We report a series of 13 patients with nonspecific anal ulceration all of whom were receiving nicorandil for control of symptoms of ischaemic heart disease.
RESULTS: All the ulcers had similar clinical and histological appearances. All the ulcers healed on withdrawal of the drug.
CONCLUSION: Nicorandil-associated anal ulceration should be considered in the differential diagnoses of nonhealing anal ulcers.
PATIENTS AND METHODS: We report a series of 13 patients with nonspecific anal ulceration all of whom were receiving nicorandil for control of symptoms of ischaemic heart disease.
RESULTS: All the ulcers had similar clinical and histological appearances. All the ulcers healed on withdrawal of the drug.
CONCLUSION: Nicorandil-associated anal ulceration should be considered in the differential diagnoses of nonhealing anal ulcers.