Vascular and endovascular surgery · 2013
Outcomes of thrombolysis with and without predilation of the inferior vena cava (IVC) in patients with Budd-Chiari syndrome with old IVC thrombosis.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Ren Jian-Zhuang, Huang Guo-Hao, Ding Peng-Xu, Wu Gang, Han Xin-Wei, Wang Yan-Li
Аннотация
PURPOSE: To compare the efficacy of thrombolysis with and without predilation of the inferior vena cava (IVC) for Budd-Chiari syndrome (BCS) with old IVC thrombosis.
METHODS: We divided 40 patients with BCS with old IVC thrombosis into 2 groups, group A (n = 21), thrombolysis after dilation of the obstructed IVC and group B (n = 19), thrombolysis without predilation of the obstructed IVC. Thrombolysis was performed via urokinase administration through the dorsal vein of the foot.
RESULTS: Color Doppler ultrasonography at 30 days showed complete resolution of the thrombus in 21 (100%) group A patients and 6 group B patients (31.6%; P < .001). Thrombolysis was achieved using a lower dose of urokinase and within a shorter time frame in group A than in group B (P < .001).
CONCLUSIONS: Thrombolysis after dilation was superior to thrombolysis alone and was safe and efficacious in patients with BCS with old IVC thrombosis.
METHODS: We divided 40 patients with BCS with old IVC thrombosis into 2 groups, group A (n = 21), thrombolysis after dilation of the obstructed IVC and group B (n = 19), thrombolysis without predilation of the obstructed IVC. Thrombolysis was performed via urokinase administration through the dorsal vein of the foot.
RESULTS: Color Doppler ultrasonography at 30 days showed complete resolution of the thrombus in 21 (100%) group A patients and 6 group B patients (31.6%; P < .001). Thrombolysis was achieved using a lower dose of urokinase and within a shorter time frame in group A than in group B (P < .001).
CONCLUSIONS: Thrombolysis after dilation was superior to thrombolysis alone and was safe and efficacious in patients with BCS with old IVC thrombosis.
Предметные рубрики MeSH
Administration, IntravenousAdultAgedAngioplasty, BalloonBudd-Chiari SyndromeChi-Square DistributionCombined Modality TherapyFemaleFibrinolytic AgentsHumansKaplan-Meier EstimateMaleMiddle AgedPhlebographyPredictive Value of TestsThrombolytic TherapyTime FactorsTreatment OutcomeUltrasonography, Doppler, ColorUrokinase-Type Plasminogen ActivatorVascular Access DevicesVena Cava, Inferior