[Morphological studies of leukocyte long-term culture. 1. A new in vitro phenomenon in the diagnosis of discoid lupus erythematosus].

A new routine-method is presented for the morphokinetic documentation of autoimmunologically induced processes in vitro via leukocyte long-term culture (LLC). The prominent rosette-sheeped autologous lymphocytes in deposition at central granulocytes are well defined. These autologous rosette-formations in LLC rank very high in diagnosis of autoimmundiseases, since this phenomenon is positive already, while the results of current methods in routine-serumexaminations are still negative. Presenting a case of discoid Lupus Erythematodes this well developed method is represented in early recognition of dermatological autoimmundiseases, while cellular cinetics are discussed.