Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2020
Male patients with neuromyelitis optica spectrum disorders: different clinical characteristics and worse steroid treatment response.
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Li Rui, Li Cong, Mao Zhifeng, Huang Qiao, Shu Yaqing, Chang Yanyu, Wang Jingqi, Wang Yuge, Qiu Wei
Аннотация
BACKGROUND: Clinical data on male neuromyelitis optica spectrum (NMO) patients remain limited to date.
OBJECTIVE: To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.
METHODS: We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.
RESULTS: We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.
CONCLUSION: Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.
OBJECTIVE: To analyze clinical characteristics, therapeutic responses, and outcomes in Chinese male NMOSD patients.
METHODS: We retrospectively assessed clinical, demographic, treatment, and outcome data of male patients with NMOSD.
RESULTS: We identified 52 male patients among 471 NMOSD patients. Male patients had more frequent optic neuritis (ON) attacks and less frequent myelitis than female patients. No-remission rates of high-dose intravenous steroid therapy were higher in male patients than in female patients.
CONCLUSION: Male NMOSD patients had different clinical characteristics and worse response to high-dose intravenous steroid therapy than female patients.