[Pathogenetic mechanisms and classification of manic-depressive psychosis].

A study of the heredity and exogenic factors in 340 patients with manic-depressive psychosis makes it possible to draw a conclusion that the disorder is polyetiological. In a bipolar development there is mainly a hereditary loading and organic noxious factors, in a monopolar depression--exhaustive factors. The assumption of an existence of 2 independent psychoses (bipolar and monopolar) which was made by several foreign authors was not confirmed.