[Bone lesions in micromegakaryoblastic leukemia].

The authors report four cases of skeletal lesions associated with acute megakaryoblastic leukemia. In this particular form of the disease, the periostal appositions are more frequent and more severe than in other types of acute leukemia. A very marked osteolysis with true metaphyseal lacunar zones are also observed. These particular types of bone lesion are related to the especially widespread cellular proliferation in megakaryoblastic leukemia, and their occurrence implies a very bad prognosis.