Targeting the malaria parasite inside the mosquito host.

Control of malaria uses a variety of tools including drugs, vaccines, and insecticidal strategies to reduce parasite transmission by mosquito vectors. A new tool that eliminates parasites in mosquitoes by delivering antimalarials to the insects rather than infected people is emerging as a simple, relatively inexpensive malaria control strategy. In this Chapter, we review antimalarials that show efficacy in mosquitoes, effective methods to deliver compounds into the insects, and strategies to optimize this new tool as a useful component of the arsenal of strategies to combat malaria.