Effect of amphotericin B and tear K+ on PD responses to changes in stromal K+ in frog cornea.

Data have been presented in this paper that support the hypothesis that normal or anomalous responses to changes in stromal K+ are a result of the relative conductances of the simple K+ and the (Na+ + K+)-ATPase pathways located in the basolateral membrane of the corneal epithelium. The simple K+ conductance may be changed by changing the tear K+ concentration in the presence of amphotericin B and by the use of Ba2+ in the stromal solution.