Annals of African medicine · 2025
Clinical and Polysomnographic Differences in Obese and Nonobese Patients with Obstructive Sleep Apnea.
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Adiody Supriya, Narayanan S Vishnu
Аннотация
BACKGROUND: Obstructive sleep apnea (OSA) is characterized by repeated episodes of upper airway obstruction during sleep, resulting in fragmented sleep and associated health risks.
OBJECTIVE: This retrospective study investigated the clinical and polysomnographic differences between obese and nonobese patients diagnosed with OSA.
METHODOLOGY: A total of 210 patients underwent a Level 3 sleep study. Based on the apnea-hypopnea index (AHI), 180 patients with OSA were included in the study. Patients were categorized as obese (body mass index [BMI] ≥27.5) or nonobese (BMI <27.5). Clinical parameters, AHI, oxygen desaturation index (ODI), Epworth Sleepiness Scale (ESS), neck circumference, age, and gender were compared.
RESULTS: Obese patients had significantly higher AHI, ODI, ESS scores, and neck circumference than nonobese patients ( P < 0.05). Gender was associated with the severity of OSA only in the obese group. Age was not significantly associated with OSA severity in either group.
DISCUSSION: Obesity is strongly associated with more severe OSA and anatomical risk factors. Nonobese OSA patients also exhibited clinically relevant symptoms, suggesting distinct nonanatomical mechanisms.
CONCLUSION: This study concludes that while obesity is linked to more severe OSA due to anatomical factors, non-obese patients also experience significant disease, highlighting the importance of individualized, phenotype-driven management strategies.
OBJECTIVE: This retrospective study investigated the clinical and polysomnographic differences between obese and nonobese patients diagnosed with OSA.
METHODOLOGY: A total of 210 patients underwent a Level 3 sleep study. Based on the apnea-hypopnea index (AHI), 180 patients with OSA were included in the study. Patients were categorized as obese (body mass index [BMI] ≥27.5) or nonobese (BMI <27.5). Clinical parameters, AHI, oxygen desaturation index (ODI), Epworth Sleepiness Scale (ESS), neck circumference, age, and gender were compared.
RESULTS: Obese patients had significantly higher AHI, ODI, ESS scores, and neck circumference than nonobese patients ( P < 0.05). Gender was associated with the severity of OSA only in the obese group. Age was not significantly associated with OSA severity in either group.
DISCUSSION: Obesity is strongly associated with more severe OSA and anatomical risk factors. Nonobese OSA patients also exhibited clinically relevant symptoms, suggesting distinct nonanatomical mechanisms.
CONCLUSION: This study concludes that while obesity is linked to more severe OSA due to anatomical factors, non-obese patients also experience significant disease, highlighting the importance of individualized, phenotype-driven management strategies.