Infection and drug resistance · 2025
The Conservative Treatment of a Rare Postoperative Complication of DBS-Brain Abscess: Case Series.
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Lu Guanghan, Liu Jingxuan, Wei Xiang, Yan Jiuqi, Sun Jian, Dong Wenwen, Zhao Liang, Qiu Chang, Luo Bei, Zhang Wenbin
Аннотация
BACKGROUND: Deep Brain Stimulation (DBS) is an established treatment option for movement disorders such as Parkinson's disease and dystonia, so more and more patients (over 160,000 patients till 2019) worldwide have undergone DBS for a variety of neurological and non-neurological conditions, with numbers increasing each year. This case series primarily discusses a very rare complication following DBS surgery -- brain abscess.
CASE PRESENTATION: We administered vancomycin and metronidazole to patients who developed brain abscesses after undergoing DBS surgery based on previous literature. After treatment, the abscess lesions and infection symptoms completely resolved, resulting in a good therapeutic outcome without the removal of the DBS system.
CONCLUSION: In previous studies, similar cases always involved surgical intervention to drain the pus while also removing the DBS system; however, in our cases, the patient did not have the DBS system removed and achieved a good prognosis. To our knowledge, our two cases are among the few where a conservative treatment approach has been used for brain abscesses after DBS surgery.
CASE PRESENTATION: We administered vancomycin and metronidazole to patients who developed brain abscesses after undergoing DBS surgery based on previous literature. After treatment, the abscess lesions and infection symptoms completely resolved, resulting in a good therapeutic outcome without the removal of the DBS system.
CONCLUSION: In previous studies, similar cases always involved surgical intervention to drain the pus while also removing the DBS system; however, in our cases, the patient did not have the DBS system removed and achieved a good prognosis. To our knowledge, our two cases are among the few where a conservative treatment approach has been used for brain abscesses after DBS surgery.