Biomarkers in medicine · 2025
Clinical relevance of HRR (hemoglobin to RDW) and RAR (RDW to albumin) in pericarditis.
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Eyiol Hatice, Eyiol Azmi, Sahin Ahmet Taha
Аннотация
AIM: This study evaluated the Hemoglobin to Red Cell Distribution Width Ratio (HRR) and Red Cell Distribution Width to Albumin Ratio (RAR) in acute pericarditis patients, exploring associations with clinical parameters.
METHODS: A retrospective cohort study included 257 patients diagnosed with acute pericarditis (2015-2023). Data on hemoglobin, RDW, albumin, treatments, hospital stay, and recurrence were analyzed using SPSS 27.0.
RESULTS: The mean age was 41 years. HRR averaged 1.067 ± 0.142, and RAR was 0.311. Men had higher hemoglobin and albumin levels, while women had higher platelet and HDL levels. Lower HRR correlated with severe conditions and recurrence, while higher RAR was linked to disease severity and recurrence. Both markers were strongly associated with pericardial effusion and IV steroid need.
CONCLUSION: HRR and RAR are valuable biomarkers in acute pericarditis, aiding in assessing disease severity and guiding treatment.
METHODS: A retrospective cohort study included 257 patients diagnosed with acute pericarditis (2015-2023). Data on hemoglobin, RDW, albumin, treatments, hospital stay, and recurrence were analyzed using SPSS 27.0.
RESULTS: The mean age was 41 years. HRR averaged 1.067 ± 0.142, and RAR was 0.311. Men had higher hemoglobin and albumin levels, while women had higher platelet and HDL levels. Lower HRR correlated with severe conditions and recurrence, while higher RAR was linked to disease severity and recurrence. Both markers were strongly associated with pericardial effusion and IV steroid need.
CONCLUSION: HRR and RAR are valuable biomarkers in acute pericarditis, aiding in assessing disease severity and guiding treatment.