Natural product research · 2019
Araçain, a tyrosol derivative and other phytochemicals from Psidium guineense Sw.
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Macaúbas-Silva Camila, Félix Maysa D G, Aquino Ana Karoline S de, Pereira-Júnior Paulo G, Brito Emmily Vieira de O, Oliveira-Filho Abrahão A de, Igoli John O, Watson David G, Teles Yanna C F
Аннотация
Psidium guineense Sw. (Myrtaceae) is a shrub distributed all over South America and Brazil. Its leaves are traditionally used to treat digestive problems and infections. Several biological activities have been reported for P. guineense extracts, however phytochemical studies are scarce. The present study is on the isolation of compounds from P. guineense leaf extracts using chromatographic and spectroscopic techniques and evaluation of their antibacterial activity. Araçain, a tyrosol derivative was isolated as a natural product for the first time. Other compounds isolated were ursolic acid, a phaeophorbide and three flavonoids. The extracts were tested for their antimicrobial activity against Klebsiella pneumoniae strains and they showed moderate to high antibacterial activity.