Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion · 2026
Association between early blood pressure variability and short-term outcomes in patients with hypertension and acute stroke: A prospective cohort study.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Li JiBo, Chen Feng, Liu ChanChan, Xu Feng
Аннотация
OBJECTIVE: To investigate the association between early blood pressure variability (BPV) and 90-day prognosis in hypertensive patients with acute stroke who did not receive reperfusion therapy.
METHODS: This prospective cohort study enrolled patients with a history of hypertension and acute stroke within 24h of onset. The main analysis cohort excluded those who received intravenous thrombolysis and/or endovascular treatment. Blood pressure was monitored within 24h after admission, and systolic blood pressure standard deviation (SBP-SD), coefficient of variation (SBP-CV), and average real variation (ARV) were calculated. According to the 90-day modified Rankin scale (mRS) score, outcomes were classified as good or poor. Subsequently, predictive variables were screened, and the impact of blood pressure variability on prognosis was assessed using a multivariate logistic regression model.
RESULTS: Higher SBP-SD and SBP-CV were independent risk factors for poor prognosis at 90 days. The prediction model incorporating BPV indicators demonstrated good discriminant ability. Patients receiving reperfusion therapy (n=18) had higher BPV levels and a lower rate of good prognosis (22.2%).
CONCLUSION: For patients with hypertension complicated with acute stroke who did not undergo reperfusion therapy, higher systolic BPV within 24h after admission is an independent predictor of 90-day poor prognosis.
METHODS: This prospective cohort study enrolled patients with a history of hypertension and acute stroke within 24h of onset. The main analysis cohort excluded those who received intravenous thrombolysis and/or endovascular treatment. Blood pressure was monitored within 24h after admission, and systolic blood pressure standard deviation (SBP-SD), coefficient of variation (SBP-CV), and average real variation (ARV) were calculated. According to the 90-day modified Rankin scale (mRS) score, outcomes were classified as good or poor. Subsequently, predictive variables were screened, and the impact of blood pressure variability on prognosis was assessed using a multivariate logistic regression model.
RESULTS: Higher SBP-SD and SBP-CV were independent risk factors for poor prognosis at 90 days. The prediction model incorporating BPV indicators demonstrated good discriminant ability. Patients receiving reperfusion therapy (n=18) had higher BPV levels and a lower rate of good prognosis (22.2%).
CONCLUSION: For patients with hypertension complicated with acute stroke who did not undergo reperfusion therapy, higher systolic BPV within 24h after admission is an independent predictor of 90-day poor prognosis.