Journal of palliative medicine · 2018
Resurgence of Eating Disorders with Olanzapine.
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Wu Kelly L, Lorenz Amanda K, Christensen Kelly J, Feely Molly A, Carey Elise C, Strand Jacob J
Аннотация
BACKGROUND: Olanzapine is commonly utilized in palliative care for the treatment of nausea, and a known side effect of olanzapine is increased appetite. Olanzapine is also known to cause re-emergence of eating disorders (EDs) in patients utilizing olanzapine for its antipsychotic effects. It is unclear to what extent this may also occur in patients with serious/life-limiting illness.
METHODS AND RESULTS: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine.
CONCLUSION: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.
METHODS AND RESULTS: We present a case of a 70-year-old female with recurrent ovarian cancer and a history of bulimia nervosa (BN) that developed resurgence of her BN after initiation of olanzapine for cancer-associated nausea. Her BN resolved with reducing the dose of olanzapine.
CONCLUSION: It is important to recognize that recurrence of EDs can occur when using olanzapine in the palliative care setting.