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DOI 10.1016/j.tracli.2022.06.001

Медицинская библиотека · Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine · 2022

Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data.

Caffrey N, Goldman M, Lewin A, Grégoire Y, Yi Q-L, O'Brien S F

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Аннотация

OBJECTIVE

Gay, bisexual and other men who have sex with men (gbMSM) were ineligible to donate blood in most countries since the 1980's. In Canada the deferral period has been incrementally decreased from lifetime to male-to-male sex in the last 3 months. Now a few countries have removed the deferral altogether. Risk models have been utilised to estimate the probability of an HIV positive donation being released into the blood supply and to inform incremental changes to the length of the deferral period. Here we use public health data to estimate the risk of HIV if the gbMSM deferral criteria were removed in Canada.

MATERIAL AND

METHODS

We calculate the risk reduction among heterosexuals based on responses to standard risk questions routinely asked of donors. We assume gbMSM will donate at the same rate as heterosexual males. We apply the same risk reduction principle to HIV incidence and prevalence among gbMSM in the general population to evaluate the HIV risk without gbMSM time deferral. We model three scenarios where risk reduction is varied by assumptions about incidence and compliance with deferral criteria.

RESULTS

The estimates for all scenarios were not significantly different to the currently observed scenario which predicts a residual risk of 0.02 HIV positive per million donations (95% CI: 0.000006-0.09).

CONCLUSION

The models predict that removing the gbMSM deferral criteria would result in HIV residual risk similar to currently observed.

Для цитирования: Caffrey N, Goldman M, Lewin A, Grégoire Y, Yi Q-L, O'Brien S F. Removing the men who have sex with men blood donation deferral: Informing risk models using Canadian public health surveillance data.. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine. 2022. DOI: 10.1016/j.tracli.2022.06.001.

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